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Geidy E. Serrano
  • Female
  • Puerto Rico
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about me
I received my doctoral degree in Anatomy from the University of Puerto Rico, Medical Science Campus. My thesis project involved the characterization of a bilateral pair of motor neurons (B67) in the feeding system of Aplysia californica, which allowed me to learn and master several electrophysiology techniques. In 2007 I received a postdoctoral appointment at Emory University’s School of Medicine with Dr. Ray Dingledine. One of the goals of the laboratory I joined is the study of basic cellular and molecular mechanisms of epilepsy
.Research Project: Epilepsy is a family of neurological disorders characterized by the unpredictable but recurrent occurrence of seizures. Previous work demonstrated that prolonged status epilepticus (SE) results in neuronal death and the rapid induction of numerous mediators of inflammation including cyclooxygenase-2 (COX2), eventually resulting in cognitive deficits, epilepsy and related functional disorders. My current project uses a conditional knockout mouse that lacks COX2 in the principal forebrain neurons as an innovative approach to determine whether the principal neurons of the hippocampus are the source of COX2 involved in neuro-pathologies observed after SE. I would like to understand the role of COX2 induction and its signaling pathways in the synaptic plasticity observed in the hippocampal network after SE. These studies will provide new information on the regulation of inhibitory synaptic plasticity in the normal and epileptic hippocampus. If interruption of SE-induced COX2 in neurons is found to be involved in the synaptic plasticity and/or selective neurodegeneration that occurs in the hippocampus after SE, these studies could lead to a strategy for interrupting epileptogenesis and impact the lives of those with epilepsy.
what is your current, past or ideal job title?
Professor and/or scientist
what languages do you speak?
English, Spanish
what countries have you lived in?
Puerto Rico, United States of America
what's your Hispanic connection?
Puerto Rican

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At 4:28pm on September 2, 2011, Don Martinez said…
visit us at www.domarrgoup.com
At 8:18pm on January 24, 2010, Andrea Byrge said…
I noticed your profile and saw that you live in New York. I work with the doctors who created Proactiv Solution and I am looking for some connections in the Latin communtity who might be interested in partnering with us as we launch our new product line in New York, Puerto Rico and nationally. If you or other professionals with your cultural background might be interested, please call me at 407-687-8268. Our corporate team will be in Puerto Rico this Wed. thru Sat.Thank you

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